21st Amendment Brewery is a brewery located in San Leandro, California. Their original location is a brewpub and restaurant in the South Park neighborhood of San Francisco, California, two blocks from Oracle Park. The brewery's name refers to the 21st Amendment to the U.S. Constitution, which repealed Prohibition. They are known for their innovative craft beers, including Hell or High Watermelon Wheat Ale and Brew Free! Or Die IPA. The brewery also offers seasonal and limited-edition beers, as well as a variety of merchandise. Their facilities include a taproom and brewery in San Leandro and a brewpub in San Francisco, both of which host events and provide a welcoming atmosphere for beer enthusiasts.